ABCB8 Polyclonal Antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

ATP binding cassette sub family B member 8; ABCB8; ABCB8; ATP binding cassette sub family B (MDR/TAP) member 8; ATP binding cassette sub family B member 8 mitochondrial; ATP-binding cassette sub-family B member 8; EST328128; M ABC1; M-ABC1; MABC1; Mitochondrial ABC protein; mitochondrial; Mitochondrial ATP binding cassette 1; Mitochondrial ATP-binding cassette 1