LTB Polyclonal Antibody
Product Specifications
Background
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
LTB
UniProt
Q06643
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human LTB
Target
LT beta; LT-beta; Ltb; lymphotoxin beta; Lymphotoxin-beta; p33; TNF-C; TNFC; TNFC; TNFSF3; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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