TMPRSS11F Polyclonal Antibody
Product Specifications
Background
TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1) . TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
Abbreviation
TMPRSS11F
UniProt
Q6ZWK6
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human TMPRSS11F
Target
Transmembrane protease serine 11F; TMPRSS11F; Airway trypsin-like protease 4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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