SLIT2 Polyclonal Antibody
Product Specifications
Background
Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.
Abbreviation
SLIT2
UniProt
O94813
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human SLIT2
Target
Drad 1; E030015M03Rik; E130320P19Rik; FLJ14420; OTTHUMP00000158695; OTTHUMP00000217852; OTTHUMP00000217853; OTTHUMP00000217854; Slil 3; Slil3; Slit 2; Slit homolog 2 (Drosophila) ; Slit homolog 2; Slit homolog 2 protein; Slit homolog 2 protein C-product; Slit-2; Slit2; SLIT2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Neuroscience
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/c8ckko
Product MSDS
https://789.bio/eb/f9i1m9
Calculated Molecular Weight
170kDa
Isotype
IgG
Available Sizes
Curated Selection
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