PUS10 Polyclonal Antibody
Product Specifications
Background
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.
Abbreviation
PUS10
UniProt
Q3MIT2
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human PUS10
Target
CCDC139; Coiled coil domain containing 139; Coiled coil domain containing protein 139; Coiled-coil domain-containing protein 139; DOBI; FLJ32312; MGC126729; Pseudouridine synthase 10; Pseudouridylate synthase 10; Psi55 synthase; pus10; PUS10; Putative tRNA pseudouridine synthase Pus10; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA uridine isomerase; tRNA-uridine isomerase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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