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PLXNA4 Polyclonal Antibody

Product Specifications

Background

Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Abbreviation

PLXNA4

UniProt

Q9HCM2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human PLXNA4

Target

FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4; plxna4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Neuroscience

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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