P2RX3 Polyclonal Antibody
Product Specifications
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Abbreviation
P2RX3
UniProt
P56373
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human P2RX3
Target
ATP receptor; MGC129956; P2rx3; P2RX3; P2X purinoceptor 3; P2X receptor subunit 3; P2X3; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 3; Purinergic receptor P2X3; Purinoceptor P2X3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa
Isotype
IgG
Available Sizes
Curated Selection
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