CYBB Polyclonal Antibody

Product Specifications

Background

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.

Abbreviation

CYBB

UniProt

P04839

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human CYBB

Target

AMCBX2; CGD; CGD91-phox; CY24B; CYBB; Cytochrome b 245; beta polypeptide; Cytochrome b (558) beta chain; Cytochrome b (558) subunit beta; Cytochrome b-245 heavy chain; Cytochrome b558 subunit beta; GP91 PHOX; gp91-1; gp91-phox; GP91PHOX; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; NOX2; p22 phagocyte B-cytochrome; P91 PHOX; p91-PHOX; Superoxide-generating NADPH oxidase heavy chain subunit