FAT1 Polyclonal Antibody

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF) -like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Cadherin family member 7; Cadherin family member 7 precursor; Cadherin ME5; Cadherin related tumor suppressor; Cadherin related tumor suppressor homolog; Cadherin related tumor suppressor homolog precursor; Cadherin related tumor suppressor homolog precursor (FAT protein homolog) ; Cadherin-related tumor suppressor homolog; CDHF 7; CDHF7; FAT 1; FAT tumor suppressor 1; FAT tumor suppressor homolog 1; FAT1; FAT1; hFat 1; hFAT; hFat1; Homolog of Drosophila FAT protein; Homolog of Drosophila FAT protein precursor; Homolog of Drosophila tumor suppressor FAT precursor; ME 5; ME5; nuclear form; Protein fat homolog; Protocadherin Fat 1