DAAM1 Polyclonal Antibody
Product Specifications
Background
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl) -Rho complex.
Abbreviation
DAAM1
UniProt
Q9Y4D1
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human DAAM1
Target
DAAM 1; Dishevelled associated activator of morphogenesis 1; FLJ41657; KIAA0666
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1.2 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
123kDa
Citation 01
https://www.mdpi.com/1422-0067/23/9/5128
Isotype
IgG
Available Sizes
Curated Selection
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