NCR2 Polyclonal Antibody

Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336 (cluster of differentiation336) . NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Activating NK receptor NKp44; CD336; CD336 antigen; dJ149M18.1; LY95; Lymphocyte antigen 95 (activating NK receptor; NK p44) ; Lymphocyte antigen 95 homolog (activating NK receptor; NK p44) ; Lymphocyte antigen 95 homolog; Lymphocyte antigen 95; mouse; homolog of; Natural cytotoxicity triggering receptor 2; Natural killer cell p44 related protein; Natural killer cell p44-related protein; NCR2; NCTR2; NK cell activating receptor (NKp44) ; NK cell activating receptor; NK cell-activating receptor; NK p44; NK-p44; NKp44