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ALDH5A1 Polyclonal Antibody

Product Specifications

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA) . In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Abbreviation

ALDH5A1

UniProt

P51649

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human ALDH5A1

Target

Aldedehyde dehydrogenase 5 family; Aldehyde dehydrogenase 5 family member A1; Aldehyde dehydrogenase 5A1; Aldehyde dehydrogenase family 5 member A1; ALDH5A 1; Aldh5a1; mitochondrial; Mitochondrial succinate semialdehyde dehydrogenase; NAD (+) dependent succinic semialdehyde dehydrogenase; NAD (+) -dependent succinic semialdehyde dehydrogenase; SSADH; SSDH; SSDH; Succinate semialdehyde dehydrogenase; Succinate-semialdehyde dehydrogenase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Metabolism; Neuroscience; Signal Transduction

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/sllzu5

Product MSDS

https://789.bio/eb/av1yP8

Isotype

IgG

Available Sizes

Curated Selection

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