TRPM5 Polyclonal Antibody

This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca (2+) ions. It is activated by lower concentrations of intracellular Ca (2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

9430099A16Rik; Long transient receptor potential channel 5; LTrpC-5; LTrpC5; MLSN1 and TRP related gene 1; MLSN1 and TRP related gene 1 protein; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; MTR1; Novel protein similar to vertebrate transient receptor potential cation channel; subfamily M; member 5; Transient receptor potential cation channel subfamily M member 5; Transient receptor potential cation channel; subfamily M; member 5; Trpm5; TRPM5 transient receptor potential cation channel; subfamily M; member 5; TRPM5