AKR1C1 Polyclonal Antibody

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

2-dihydrobenzene-1;2-diol dehydrogenase;20 alpha (3 alpha) hydroxysteroid dehydrogenase;20 ALPHA HSD;20 alpha hydroxysteroid dehydrogenase;20-alpha-HSD;20-alpha-hydroxysteroid dehydrogenase;20ALPHAHSD;2ALPHAHSD; AK1C1; AK1C1; AKR1C1; Aldo keto reductase family 1 member C1; aldo-keto reductase C; Aldo-keto reductase family 1 member C1; Aldo-keto reductase family;1 member 1; C9; Chlordecone reductase homolog; Chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1;20-alpha (3-alpha) -hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; Dihydrodiol dehydrogenase; type 1; H37; HAKRC; HBAB; Hepatic dihydrodiol dehydrogenase; High affinity hepatic bile acid-binding protein; High-affinity hepatic bile acid-binding protein; Indanol dehydrogenase; MBAB; MGC8954; Trans-1; Trans-1;2 dihydrobenzene 1;2 diol dehydrogenase; Type II 3 alpha hydroxysteroid dehydrogenase