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14-3-3 theta Polyclonal Antibody

Product Specifications

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Abbreviation

YWHAQ

UniProt

P27348

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human YWHAQ

Target

14 3 3 protein T cell;14 3 3 protein tau;14 3 3 protein theta;14 3 3 tau;14 3 3 theta;14-3-3 protein T-cell;14-3-3 protein tau;14-3-3 protein theta;1433T;1C5; HS1; KCIP1; Protein HS1; Protein kinase C inhibitor protein 1; Protein tau; tyr3/trp5 monooxygenase activation protein; theta; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; theta polypeptide; Ywhaq

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

28kDa

Isotype

IgG

Available Sizes

Curated Selection

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