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IL2RA Polyclonal Antibody

Product Specifications

Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Abbreviation

IL2RA

UniProt

P01589

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human IL2RA

Target

Interleukin 2 receptor alpha chain; CD25; CD25 antigen; IDDM10; IL 2 receptor alpha subunit; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2 RA; IL2-RA; IL2R; IL2R; alpha chain; IL2RA; IL2RA; IMD41; Interleukin 2 receptor alpha; Interleukin 2 receptor; Interleukin-2 receptor subunit alpha; p55; t-cell growth factor receptor; TAC; TAC antigen; TCGFR

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Immunology

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:200-1:1000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

31kDa

Isotype

IgG

Available Sizes

Curated Selection

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