PKD1 Polyclonal Antibody

This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1) .

Autosomal dominant polycystic kidney disease 1 protein; Autosomal dominant polycystic kidney disease protein 1; nPKC-D1; nPKC-mu; OTTHUMP00000208669; OTTHUMP00000208670; PBP; Pc-1; PKD; Pkd1; PKD1; Polycystic Kidney Disease 1; polycystic kidney disease-associated protein; Polycystin 1 Precursor; Polycystin-1; Protein kinase C mu type; Protein kinase D; Serine/threonine-protein kinase D1; transient receptor potential cation channel; subfamily P; member 1; TRPP1