BCL2 Polyclonal Antibody

Product Specifications

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Abbreviation

BCL2

UniProt

P10415

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human BCL2

Target

Apoptosis regulator Bcl 2; Apoptosis regulator Bcl-2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; Bcl-2; Bcl2; BCL2; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; B-cell;2; Oncogene B-cell leukemia 2; PPP1R50; Protein phosphatase 1; regulatory subunit 50

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cell Biology; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0269749122002627

Citation 02

https://www.mdpi.com/2072-6694/12/2/435/htm

Citation 03

https://www.mdpi.com/article/10.3390/plants12030529

Citation 04

https://www.tandfonline.com/doi/abs/10.1080/13880209.2020.1765812

Citation 05

https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-020-03120-1

Citation 06

https://link.springer.com/article/10.1007/s12011-018-1535-3

Citation 07

https://www.sciencedirect.com/science/article/pii/S006512812030129X

Isotype

IgG

Available Sizes

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