ADRA1B Polyclonal Antibody

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

ADA1B; ADRA 1; Adra 1b; ADRA1; ADRA1B; Adrenergic alpha 1B receptor; Adrenergic receptor alpha 1b; Adrenoceptor alpha 1B; Alpha 1 adrenergic receptor; Alpha 1B adrenoceptor; Alpha 1B adrenoreceptor; Alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; Alpha-1B adrenoreceptor; Alpha1 adrenergic receptor; Alpha1B adrenergic receptor; Alpha1BAR