RGS1 Polyclonal Antibody

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

1R20; B cell activation protein BL34; B-cell activation protein BL34; BL34; Early response protein 1R20; IER 1; IER1; Immediate early response 1 B cell specific; immediate-early response 1; B-cell specific; IR20; Regulator of G protein signalling 1; Regulator of G-protein signaling 1; RGS 1; RGS1; RGS1