PYGL Polyclonal Antibody
Product Specifications
Background
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
Abbreviation
PYGL
UniProt
P06737
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PYGL
Target
Glycogen phosphorylase; Glycogen phosphorylase L; Glycogen phosphorylase liver; Glycogen phosphorylase liver form; GSD6; Hers disease; glycogen storage disease type VI; liver form; OTTHUMP00000233649; OTTHUMP00000233651; Phosphorylase glycogen liver; Pygl; PYGL
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/wsoog4
Product MSDS
https://789.bio/eb/jH8GCO
Calculated Molecular Weight
97kDa
Isotype
IgG
Available Sizes
Curated Selection
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