PAICS Polyclonal Antibody
Product Specifications
Background
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
PAICS
UniProt
P22234
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PAICS
Target
ADE2; ADE2H1; AIR carboxylase; AIRC; DKFZp781N1372; MGC1343; MGC5024; Multifunctional protein ADE2; Multifunctional protein ADE2H1; Paics; PAIS; Phosphoribosylaminoimidazole carboxylase; Phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazole succinocarboxamide synthetase; PUR6; SAICAR synthetase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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