MVK Polyclonal Antibody
Product Specifications
Background
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.
Abbreviation
MVK
UniProt
Q03426
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human MVK
Target
FLJ96772; KIME; LH receptor mRNA binding protein; LRBP; Mevalonate kinase 1; Mevalonate kinase; Mevalonic aciduria; MK; mvk; MVLK; POROK3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/o4gcgk
Product MSDS
https://789.bio/eb/n5WDmP
Calculated Molecular Weight
42kDa
Isotype
IgG
Available Sizes
Curated Selection
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