HSD17B2 Polyclonal Antibody

17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

17 beta HSD 2;17-beta-HSD 2;17-beta-hydroxysteroid dehydrogenase type 2;20 alpha HSD;20 alpha hydroxysteroid dehydrogenase;20 alpha-hydroxysteroid dehydrogenase;20-alpha-HSD; DHB2; E2DH; EDH17B2; Estradiol 17-beta-dehydrogenase 2; HSD17; Hsd17b2; Hydroxysteroid (17 beta) dehydrogenase 2; Microsomal 17 beta hydroxysteroid dehydrogenase; Microsomal 17-beta-hydroxysteroid dehydrogenase; SDR9C2; Short chain dehydrogenase/reductase family 9C; member 2; Testosterone 17 beta dehydrogenase; Testosterone 17-beta-dehydrogenase