HSD17B12 Polyclonal Antibody
Product Specifications
Background
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.
Abbreviation
HSD17B12
UniProt
Q53GQ0
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human HSD17B12
Target
12;3-ketoacyl-CoA reductase; short chain;17 beta HSD 12;17 beta hydroxysteroid dehydrogenase 12;17-@beta-HSD XII;17-@beta-hydroxysteroid dehydrogenase XII;17-beta-HSD 12;17-beta-hydroxysteroid dehydrogenase 12;17beta HSD type 12;3 ketoacyl CoA reductase;3-ketoacyl-CoA reductase; DHB12; Estradiol 17 beta dehydrogenase 12; Estradiol 17-beta-dehydrogenase 12; HSD17B12; Hydroxysteroid (17-beta) dehydrogenase 12; KAR; KIK-I; Kik1; SDR12C1; Short chain dehydrogenase/reductase family 12C member 1; Steroid dehydrogenase homolog
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Isotype
IgG
Available Sizes
Curated Selection
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