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HSD17B8 Polyclonal Antibody

Product Specifications

Background

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Abbreviation

HSD17B8

UniProt

Q92506

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human HSD17B8

Target

17 beta HSD 8;17 beta hydroxysteroid dehydrogenase 8;17-beta-HSD 8;17-beta-hydroxysteroid dehydrogenase 8;17-beta-hydroxysteroid dehydrogenase VIII;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-acyl-carrier protein reductase; E. coli; homolog of; Beta ketoacyl [acyl carrier protein] reductase like; D6S2245E; DHB8; dJ1033B10.9; Estradiol 17 beta dehydrogenase 8; Estradiol 17-beta-dehydrogenase 8; Estrogen 17 oxidoreductase; FABG; FabG; E. coli; homolog of; FabG-like; FABGL; H2 KE6; H2-KE6; HKE6; HSD17B8; Hydroxysteroid (17 beta) dehydrogenase 8; Ke-6; KE6; KE6; mouse homolog of; Protein Ke6; Really interesting new gene 2 protein; RING2; SDR30C1; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17 beta dehydrogenase 8; Testosterone 17-beta-dehydrogenase 8

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal Transduction

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

27kDa

Isotype

IgG

Available Sizes

Curated Selection

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