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FTO Polyclonal Antibody

Product Specifications

Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Abbreviation

FTO

UniProt

Q9C0B1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human FTO

Target

AlkB homolog 9; ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; Fat mass and obesity-associated protein; FATSO; MOUSE; HOMOLOG OF; Fto; FTO; GDFD; KIAA1752; mKIAA1752; Protein fatso

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

58kDa

Isotype

IgG

Available Sizes

Curated Selection

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