EDA2R Polyclonal Antibody

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

9430060M22Rik; Ectodysplasin A2 isoform receptor; Ectodysplasin A2 receptor; EDA A2R; EDA-A2 receptor; EDA2R; EDAA2R; MGC124099; OTTMUSP00000019574; OTTMUSP00000019575; RP23-188N15.1; TNFRSF27; TNR27; Tumor necrosis factor receptor superfamily member 27; Tumor necrosis factor receptor superfamily member XEDAR; X linked ectodysplasin A2 receptor; X linked ectodysplasin receptor; X-linked ectodysplasin-A2 receptor; XEDAR