PLEKHO1 Polyclonal Antibody
Product Specifications
Background
Pleckstrin homology domain-containing family O member 1is aproteinthat in humans is encoded by thePLEKHO1gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) . May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2) . Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.
Abbreviation
PLEKHO1
UniProt
Q53GL0
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PLEKHO1
Target
C-Jun-binding protein; Casein kinase 2-interacting protein 1; CK2 interacting protein 1; CK2 interacting protein 1 HQ0024c protein; CK2-interacting protein 1; CKIP 1; CKIP-1; CKIP1; JBP; OC120; Osteoclast maturation associated gene 120 protein; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; PKHO1; Pleckstrin homology domain containing family O member 1; Pleckstrin homology domain-containing family O member 1; PLEKHO1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Isotype
IgG
Available Sizes
Curated Selection
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