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PLEKHO1 Polyclonal Antibody

Product Specifications

Background

Pleckstrin homology domain-containing family O member 1is aproteinthat in humans is encoded by thePLEKHO1gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) . May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2) . Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.

Abbreviation

PLEKHO1

UniProt

Q53GL0

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human PLEKHO1

Target

C-Jun-binding protein; Casein kinase 2-interacting protein 1; CK2 interacting protein 1; CK2 interacting protein 1 HQ0024c protein; CK2-interacting protein 1; CKIP 1; CKIP-1; CKIP1; JBP; OC120; Osteoclast maturation associated gene 120 protein; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; PKHO1; Pleckstrin homology domain containing family O member 1; Pleckstrin homology domain-containing family O member 1; PLEKHO1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:200-1:1000; IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

46kDa

Isotype

IgG

Available Sizes

Curated Selection

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