CCDC106 Polyclonal Antibody
Product Specifications
Background
The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Abbreviation
CCDC106
UniProt
Q9BWC9
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human CCDC106
Target
CC106; Ccdc106; Coiled-coil domain-containing protein 106; HSU79303; Protein predicted by clone 23882; ZNF581
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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