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ASB8 Polyclonal Antibody

Product Specifications

Background

ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

Abbreviation

ASB8

UniProt

Q9H765

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human ASB8

Target

Ankyrin repeat and SOCS box containing 8; Ankyrin repeat and SOCS box protein 8; ASB 8; ASB-8; ASB8; ASB8; FLJ21255; MGC5540; OTTHUMP00000237000; OTTHUMP00000237001; OTTHUMP00000237007; OTTHUMP00000237009; OTTHUMP00000237010; PP14212

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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