GPM6A Polyclonal Antibody
Product Specifications
Background
Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs) ; enhances internalization and recycling of mu-type opioid receptor.
Abbreviation
GPM6A
UniProt
P51674
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human GPM6A
Target
GPM6A; GPM6A; M6a; Neuronal membrane glycoprotein M6-a; Neuronal membrane glycoprotein M6-a
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31kDa
Isotype
IgG
Available Sizes
Curated Selection
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