PIM2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
Abbreviation
PIM2
UniProt
Q9P1W9
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human PIM2
Target
OTTHUMP00000025825; Pim 2 oncogene; Pim 2h; Pim-2h; PIM2; PIM2 Oncogene; PIM2; Pim2h; Proto Oncogene PIM2; Proto-oncogene Pim-2 (serine threonine kinase) ; Serine/threonine kinase PIM2; Serine/threonine-protein kinase Pim-2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/upk4kr
Product MSDS
https://789.bio/eb/eLaX94
Isotype
IgG
Available Sizes
Curated Selection
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