ACMSD Polyclonal Antibody
Product Specifications
Background
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS) . ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Abbreviation
ACMSD
UniProt
Q8TDX5
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human ACMSD
Target
2 amino 3 carboxymuconate 6 semialdehyde decarboxylase;2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; acmsd; ACMSD; Aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38kDa
Isotype
IgG
Available Sizes
Curated Selection
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