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NRN1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI) -anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.

Abbreviation

NRN1

UniProt

Q9NPD7

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human NRN1

Target

Neuritin 1; Neuritin; NRN; Nrn1; NRN1; OTTHUMP00000015989; RP3 380B8.2 protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Neuroscience

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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