MLH1 Polyclonal Antibody
Product Specifications
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Abbreviation
MLH1
UniProt
P40692
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human MLH1
Target
COCA 2; COCA2; DNA mismatch repair protein Mlh1; FCC 2; FCC2; hMLH 1; hMLH1; HNPCC 2; HNPCC; HNPCC2; MGC5172; MLH 1; MLH1; MLH1; MutL homolog 1 (E. coli) ; MutL homolog 1; MutL homolog 1 colon cancer nonpolyposis type 2; MutL homolog 1; colon cancer; nonpolyposis type 2 (E. coli) ; MutL protein homolog 1; MutL; E. coli; homolog of;1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15309896 1 Vial
Lentiviral human ZSWIM7 shRNA (UAS) - Lentiviral human ZSWIM7 shRNA (UAS) (25)
Sign In for Pricing
View Details 
MBS6283917-01 0.2 mL
CDC42, ID (CDC42, Cell division control protein 42 homolog, G25K GTP-binding protein) (PE)
Sign In for Pricing
View Details MBS6283917-02 5x 0.2 mL
CDC42, ID (CDC42, Cell division control protein 42 homolog, G25K GTP-binding protein) (PE)
Sign In for Pricing
View Details