MVP Polyclonal Antibody

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

LRP; Lung resistance related protein; Lung resistance-related protein; Major vault protein; Major vault protein; rat; homolog of; MVP; MVP; testicular secretory protein Li 30; VAULT 1; VAULT1