DOK1 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Abbreviation
DOK1
UniProt
Q99704
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human DOK1
Target
Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK1; Downstream of tyrosine kinase 1; p62 (dok) ; P62DOK; pp62
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52kDa
Isotype
IgG
Available Sizes
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