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DKK2 Polyclonal Antibody

Product Specifications

Background

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6) .

Abbreviation

DKK2

UniProt

Q9UBU2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human DKK2

Target

Dickkopf 2; Dickkopf gene 2 ; Dickkopf homolog 2; Dickkopf related protein 2; Dickkopf WNT signaling pathway inhibitor 2; Dickkopf-2; Dickkopf-related protein 2; Dickkopf2; DKK 2; Dkk-2; Dkk2; DKK2; hDkk 2; hDkk-2; hDkk2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Stem Cells

Purification

Affinity purification

Concentration

0.8 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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