Cathepsin E Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Abbreviation
CTSE
UniProt
P14091
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human CTSE
Target
CATE; CATE; Cathepsin E; Cathepsin E form II; CTSE; Erythrocyte membrane aspartic proteinase; Slow moving proteinase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Immunology
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43kDa
Isotype
IgG
Available Sizes
Curated Selection
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