AARS2 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA (Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA (Ala) . Also edits incorrectly charged tRNA (Ala) via its editing domain
Abbreviation
AARS2
UniProt
Q5JTZ9
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human AARS2
Target
AARS 2; AARS2; AARSL; Alanine tRNA ligase 2 mitochondrial; Alanine tRNA ligase; Alanyl tRNA synthetase 2 mitochondrial; Alanyl tRNA synthetase like; AlaRS; bA444E17.1; COXPD8; Gm89; KIAA1270; LKENP; MGC69820; MT ALARS; MTALARS; Probable alanyl tRNA synthetase mitochondrial; RP11-444E17.1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
107kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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