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AARS2 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA (Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA (Ala) . Also edits incorrectly charged tRNA (Ala) via its editing domain

Abbreviation

AARS2

UniProt

Q5JTZ9

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human AARS2

Target

AARS 2; AARS2; AARSL; Alanine tRNA ligase 2 mitochondrial; Alanine tRNA ligase; Alanyl tRNA synthetase 2 mitochondrial; Alanyl tRNA synthetase like; AlaRS; bA444E17.1; COXPD8; Gm89; KIAA1270; LKENP; MGC69820; MT ALARS; MTALARS; Probable alanyl tRNA synthetase mitochondrial; RP11-444E17.1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/huasr8

Product MSDS

https://789.bio/eb/ybDuzL

Calculated Molecular Weight

107kDa

Isotype

IgG

Available Sizes

Curated Selection

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