BAK1 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Abbreviation
BAK1
UniProt
Q16611
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human BAK1
Target
Apoptosis regulator BAK; BAK; BAK like; Bak NT; BAK; Bak1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl-2 homologous antagonist/killer; Bcl-2-like protein 7; BCL2 antagonist/killer 1; Bcl2 like 7 Protein; Bcl2-L-7; BCL2L7; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/8pd0cc
Product MSDS
https://789.bio/eb/fbPO80
Calculated Molecular Weight
23kDa
Citation 01
http://ar.iiarjournals.org/content/40/12/6723.short
Isotype
IgG
Available Sizes
Curated Selection
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