TONSL Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Abbreviation
TONSL
UniProt
Q96HA7
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human TONSL
Target
I kappa B related protein; I-kappa-B-related protein; IkappaBR; IKBR; Inhibitor of kappa B related protein; Inhibitor of kappa B-related protein; MMS22L-interacting protein; MMS22L-interacting protein; NFBIL2/TONSL; NF kappa B inhibitor like protein 2; NF-kappa-B inhibitor-like protein 2; NFBIL2; NFBIL2/TONSL; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; Protein IkappaBR; Tonsl; TONSL; Tonsoku-like protein; tonsoku-like; DNA repair protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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