MMP13 Polyclonal Antibody
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Abbreviation
MMP13
UniProt
P45452
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human MMP13
Target
CLG 3; CLG3; Collagenase 3; Collagenase3; MANDP1; Matrix metallopeptidase 13 (collagenase 3) ; Matrix Metalloproteinase 13; Matrix metalloproteinase-13; MMP 13; MMP-13; Mmp13; MMP13
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Cardiovascular; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/okgck8
Product MSDS
https://789.bio/eb/vnHuv1
Calculated Molecular Weight
54kDa
Citation 01
https://link.springer.com/article/10.1007/s11010-019-03655-z
Isotype
IgG
Available Sizes
Curated Selection
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