ML388
ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC50 of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells[1].
Product Specifications
CAS Number
[1537192-31-6]
UNSPSC
12352005
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml388.html
Smiles
CC1=CC=C(C=C1)N2C(C)=C(C=C2C)C3=NN=C4N3CCCCC4
Molecular Formula
C20H24N4
Molecular Weight
320.43
References & Citations
[1]Damien Y. Duveau, et al. Discovery of two small molecule inhibitors, ML387 and ML388, of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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