Recombinant Human Fragile X mental retardation syndrome-related protein 1 (FXR1), partial
Product Specifications
Product Name Alternative
(FMR1 autosomal homolog 1) (hFXR1p)
Abbreviation
Recombinant Human FXR1 protein, partial
Gene Name
FXR1
UniProt
P51114
Expression Region
123-199aa
Organism
Homo sapiens (Human)
Target Sequence
KNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLM
Tag
C-terminal 6xHis-tagged
Type
In Stock Protein
Source
E.coli
Field of Research
Epigenetics and Nuclear Signaling
Relevance
RNA-binding protein required for embryonic and postnatal development of muscle tissue . May regulate intracellular transport and local translation of certain mRNAs .
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
9.8 kDa
References & Citations
"Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy." Estan M.C., Fernandez-Nunez E., Zaki M.S., Esteban M.I., Donkervoort S., Hawkins C., Caparros-Martin J.A., Saade D., Hu Y., Bolduc V., Chao K.R., Nevado J., Lamuedra A., Largo R., Herrero-Beaumont G., Regadera J., Hernandez-Chico C., Tizzano E.F. Ruiz-Perez V.L. Nat. Commun. 10:797-797 (2019)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Product MSDS
https://www.cusabio.com/msds/12933560/
Protein Length
Partial
Available Sizes
Curated Selection
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