Mal-amido- (CH2COOH) 2

Mal-amido- (CH2COOH) 2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1].

Product Specifications

CAS Number

[207613-14-7]

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-amido-ch2cooh-2.html

Purity

99.15

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)CN(CC(O)=O)C(CCN1C(C=CC1=O)=O)=O

Molecular Formula

C11H12N2O7

Molecular Weight

284.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Dubowchik GM, et al. Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.Bioorg Med Chem Lett. 2002 Jun 3;12 (11) :1529-32.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Available Sizes

Curated Selection

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