Mal-amido- (CH2COOH) 2
Mal-amido- (CH2COOH) 2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1].
Product Specifications
CAS Number
[207613-14-7]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-amido-ch2cooh-2.html
Purity
99.15
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CN(CC(O)=O)C(CCN1C(C=CC1=O)=O)=O
Molecular Formula
C11H12N2O7
Molecular Weight
284.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Dubowchik GM, et al. Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.Bioorg Med Chem Lett. 2002 Jun 3;12 (11) :1529-32.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
136255 50 µL
Mknk1 (Mknk1, Mnk1, MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-interacting kinase 1) discontinued
Ask
View Details 
LS008540-100ug 100 µg
Alkyl DHAP synthase (AGPS) (NM_003659) Human Over-expression Lysate
Ask
View Details 