APC Anti-Human CD123 Antibody[HI12H7]
Product Specifications
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Abbreviation
CD123
Gene ID
3563
UniProt
P26951
Host
Mouse
Reactivity
Human
Target
IL-3Rα; IL-5Receptoralpha
Clonality
Monoclonal
Clone
HI12H7
Conjugation
APC
Applications
FCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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