Purified Anti-Human CD34 Antibody[4H11]
Product Specifications
Background
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
Abbreviation
CD34
Gene ID
947
UniProt
P28906
Host
Mouse
Reactivity
Human
Target
My10; Gp105-120
Clonality
Monoclonal
Clone
4H11
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cell Biology; Immunology; Neuroinflammation; Neuroscience; Stem Cells
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Citation 01
https://www.tandfonline.com/doi/abs/10.2147/DDDT.S482969
Citation 02
https://www.sciencedirect.com/science/article/pii/S0040816623001854
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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